#kidney function

Blood Q Creatinine Based on Sex and Age in Healthy Indonesian Geriatrics

ABSTRACT Median blood creatinine (Qcr) is necessary for an accurate evaluation of geriatric renal function. Nonetheless, there is a significant void in existing literature concerning creatinine reference data unique to the elderly. To improve diagnostic precision and clinical decision-making in this susceptible group, this study developed a corresponding Q model for serum creatinine in geriatric patients stratified by age and sex. To determine the Qcr serum and reference range creatinine concentrations, 913 healthy elderly patients (452 males and 461 females) undergoing routine examinations at clinical laboratories were studied. Creatinine concentration reference intervals were divided into 3 age groups, namely: 60-69 years, 70-79 years, and >80 years. The median and percentiles p2.5 (lower reference limit/LRL) and p97.5 (upper reference limit/URL) were determined by the study.

The varied Q creatinine in multi ethnics population and impact of adopting three different estimated glomerular filtration rates based on creatinine in adult populations: a call for performance validation

Background: The determination of kidney function is commonly done by estimating the glomerular filtration rate (eGFR) using serum creatinine levels. Various eGFR formulas, including the recently developed European Kidney Function Consortium (EKFC) and the Chronic Kidney Disease Epidemiology Collaboration(CKD-EPI), have been adopted and are commonly utilized in clinical settings. Nevertheless, the extent of acceptance among these formulations in the multi ethnics populace is still undetermined. Thus, this study aimed to evaluate the performance of these formulations across different glomerular filtration rate categories in the adult population. Methods: The research involved a total of 9,557 individuals (median age of 40 years and 85% being male) who underwent routine medical examinations. Enzymatic or modified Jaffe techniques were employed to measure serum creatinine levels.